Evaluation of Argyreia nervosa Seeds as Contact Spermicidal Agent

Evaluation of Argyreia nervosa Seeds as Contact Spermicidal Agent

Details of an academic research which could pave the way for future development of a potent contact spermicidal agent

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In the present study, contraceptive efficacy of different solvent based extracts of seeds of the plant Argyreia nervosa was evaluated by a series of in-vitro experiments. After contact with semen sample, there was a progressive decrease in the number of viable sperm cells. Effect of sperm mobility sperm viability, hypoosmotic swelling test were evaluated in the present study. Eosin-Nigrosin staining of the extract treated semen suspension also revealed a significant increase in the number of immotile/dead sperm cell. FTIR-ATR analysis of the extracts was carried out. It was interesting to obse...