This special issue of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.
This special issue of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.
Dr Guillaume Chanfreau obtained his Bachelor Degree from Université Claude Bernard Lyon and ENS Lyon and his PhD in Microbiology from Université Paris VI. During his PhD, mentored by Alain Jacquier, he characterized the mechanism of splicing of group II intron ribozymes. Dr Chanfreau then completed postdoctoral training at UCSF with Christine Guthrie, where he identified novel factors involved in 3'-end processing of mRNAs and small RNAs. After this postdoctoral training, he was recruited at UCLA as a professor in the Department of Chemistry and Biochemistry where he teaches a Biochemistry upper division course focused on DNA, RNA and protein synthesis. At UCLA, Dr Chanfreau has developed a research program focused on understanding the mechanisms of RNA degradation and RNA processing, and how these processes contribute to regulate gene expression.
Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997.
Inhaltsangabe
Biochemistry and Function of RNA Exosomes
Michal Lubas, Aleksander Chlebowski, Andrzej Dziembowski and Torben Heick Jensen
Plant Exosomes and Cofactors
Heike Lange and Dominique Gagliardi
Structure and Activities of the Eukaryotic RNA Exosome
Elizabeth V. Wasmuth and Christopher D. Lima
TRAMP Stimulation of Exosome
Peter Holub and Stepanka Vanacova
XRN1: A Major 5' to 3' Exoribonuclease in Eukaryotic Cells
Sarah Geisler and Jeff Coller
Structures of 5'-3' Exoribonucleases (XRNs)
Jeong Ho Chang, Song Xiang and Liang Tong
The Diverse Functions of the Nuclear Rat1/Xrn2 Exonuclease
Michal Krzyszton, Monika Zakrzewska-Placzek, Michal Koper and Joanna Kufel
Normal and Aberrantly Capped mRNA Decapping
Megerditch Kiledjian, Mi Zhou and Xinfu Jiao
Activity and Function of Deadenylases
Christiane Harnisch, Bodo Moritz, Christiane Rammelt, Claudia Temme and Elmar Wahle
The Diverse Functions of Fungal RNase III Enzymes in RNA Metabolism
