Energy Landscapes of Protein Folding: From Structure to Function
Christian Löw
Broschiertes Buch

Energy Landscapes of Protein Folding: From Structure to Function

Structure and Function of Intermediate States of Ankyrin Repeat Proteins

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Proteins are the vital molecules in living cells and important targets for pharmaceutical and biotechnological applications. To function, they need a defined three dimensional structure. All the information necessary for a protein to achieve this conformation is encoded in its amino acid sequence. To understand the process by which a polypeptide chain folds into its three-dimensional structure (the so-called "protein folding reaction") is an essential element in structural biology. This work mainly focusses on the structural and functional characterization of partially folded intermediate stat...