Effect of Statins and/or Gamma-Radiation on Tumor Cell Line
Ibrahim Abdelrahman
Broschiertes Buch

Effect of Statins and/or Gamma-Radiation on Tumor Cell Line

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The present study was conducted to investigate the effect of Gamma-radiation alone and/or combined with cytotoxic drug (Simvastatin) on the viability and the life cycle of myeloma cells. In preliminary study, Seventeen groups were designed to select three doses of Gamma-radiation from eight doses and one dose of Simvastatin from six doses in addition to three control groups. The results indicated that the dose of Simvastatin (0.1miM/l) given 24hr prior to Gamma- irradiation(0.5Gy) elevated the percentage of cell death to 37.5% as compared to 4.81% in case of radiation alone. It was found that,...