Eco-Genetic Investigation of Neural Tube Defects

Eco-Genetic Investigation of Neural Tube Defects

North Indian Population

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The neural tube defects observed during the present investigation revealed a spectrum of congenital abnormalities such as spina bifida, meningocele, meningomyelocele, lipomeningocele and encephalocele with variable clinical and morphological presentations. The epidemiological factors like maternal age, abortion (induced or spontaneous), parity, nutrition, occupation, habitation, smoking/alcoholic, medication and sex of the proband have been analyzed. Biochemically, the variations in the blood serum protein fractions of proband and their mothers were investigated. Variations in the concentratio...