Eco-Friendly Synthesis of Multi-Component Reactions

Eco-Friendly Synthesis of Multi-Component Reactions

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Organic synthesis involving less environmentally unfriendly processes and under solvent-free conditions has been investigated worldwide due to stringent environment and economic regulations. The characteristic aspect of MCRs is that the final products contain almost all portions of substrates, generating almost no by-products. That makes MCRs an extremely ideal and eco-friendly reaction system. Target molecule can be obtained in one pot with much fewer steps. Therefore, MCRs have been paid much attention in various research fields, such as discovery of lead compounds in medicinal chemistry or ...