Drosophila Melanogaster - Biosensors of Atmospheric Oxidative Stress
Malinda Wilson
Broschiertes Buch

Drosophila Melanogaster - Biosensors of Atmospheric Oxidative Stress

Drosophila Melanogaster as a Model Organism for Understanding the Interrelationship of Micronutrient Antioxidants and Atmospheric Oxidative Stress

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Studies of Drosophila melanogaster have led to molecular insights concerning biomolecular mechanisms of biology and disease including development, differentiation, cancer and aging. Wild-type Drosophila, unlike vertebrate mammals, selectively retains gamma-tocopherol over alpha-tocopherol. Urate-deficient Drosophila compared to wild-type had similar levels of glutathione but only 50% of the ascorbate levels. Dietary supplementation with ascorbate dramatically increased its level while chemically-defined diets led to rapid depletion of ascorbate in both strains. It is concluded that Drosophila ...