DNA Solution Structure Dynamics
Manish Biyani
Broschiertes Buch

DNA Solution Structure Dynamics

Single-strand conformation polymorphism at the oligodeoxyribonucleotide level

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Studies on the solution structure dynamics of RNA/DNA are becoming crucially important. The phenomena of SSCP (single-strand conformation polymorphism), microRNA dynamics in a cell, and others can be related to the conformational changes of single-stranded (ss) RNAs/DNAs in solution. These molecule, which no longer forms a helix, can adopt many different conformations in solution. What are typical conformations of these molecules and what factors govern their conformational space? To answer these important biological questions we need to explore the three broad areas: 1) How does the shape of ...