
DNA adduct
Molecular genetics, DNA, Covalent bond, Carcinogenesis, Biomarker
Herausgegeben: Victorino, Terrence James
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In molecular genetics, a DNA adduct is a piece of DNA covalently bonded to a (cancer-causing) chemical. This process could be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as biomarkers of exposure and as such are themselves measured to reflect quantitatively, for comparison, the amount of carcinogen exposure to the subject organism, i.e. rats or other living animals.