Disruption of Protein-Protein Interfaces
Broschiertes Buch

Disruption of Protein-Protein Interfaces

In Search of New Inhibitors

Herausgegeben: Mangani, Stefano
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"Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the development of useful new drugs. Consequently, in recent years great effort has been dedicated to unveiling the molecular details of protein-protein interfaces by structural techniques e.g. X-ray diffracti...