
Dipeptidyl Peptidase IV Inhibitors for Management of Type 2 Diabetes
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This book provides detailed summary about Dipeptidyl Peptidase IV (DPP IV) Inhibitors in Management of Type 2 Diabetes. DPP IV inhibitors are established therapy for managing blood glucose in patients with type 2 diabetes. Several DPP IV inhibitors are developed in last few years and are used clinically all over the world. This book describes role of Glucagon Like Peptide-1 (GLP-1), an incretin hormone in insulin secretion and how DPP IV inhibitors affect action of GLP-1. It is followed by chemistry of DPP IV inhibitors and their lead optimization strategies for clinical development.