DFT Study of Formamide and Thioformamide Oxidation by Xanthine Oxidase

DFT Study of Formamide and Thioformamide Oxidation by Xanthine Oxidase

Versandkostenfrei!
Versandfertig in 6-10 Tagen
36,99 €
inkl. MwSt.
PAYBACK Punkte
18 °P sammeln!
This text presents a rigorous mathematical account of the principles of computational chemistry in biophysical chemistry, in particular as applied to search novel xanthine oxidase inhibitors with fewer side effects and potent activities in drug design for the treatment of gout. The hydroxylation of purines is catalyzed by xanthine oxidase and purines degrade to adenosine triphosphate (ATP) which leads to accumulation of adenosine diphosphate (ADP) and adenosine monophosphate (AMP), which further degrade to uric acid which in more levels causes gout. Therefore, Inhibition of xanthine oxidase re...