Developmental Origins of Health and Disease (DOHaD)
Gebundenes Buch

Developmental Origins of Health and Disease (DOHaD)

From Biological Basis to Clinical Significance

Herausgegeben: Kubota, Takeo; Fukuoka, Hideoki
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This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonat...