Pavel Nikolov
Broschiertes Buch

Development of Three-dimensional Cell Cultures in Film-based Microdevices

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The microthermoforming and respectively the SMART technology (Substrate Modification And Replication via Thermoforming) have proven to be a useful tool, which enables the fabrication of highly defined and reproducible polymer microchips with various depths and shapes. The microthermoforming and its modifications have facilitated development of configurations, which reflect relevant aspects of the in vivo conditions, with respect to morphology and essential biochemical and biophysical cues from the microenvironment or ¿niche¿. The film-based microstructures have unique properties such as smal...