Development of Antiviral Innate Immunity in Mouse Embryonic Stem Cells
Ruoxing WangYan-Lin Guo
Broschiertes Buch

Development of Antiviral Innate Immunity in Mouse Embryonic Stem Cells

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Embryonic stem cells have been recognized as a promising cell source for regenerative medicine. However, increasing evidence indicates that ESC-derived cells generated by the current differentiation methods are not fully functional. It is recently recognized that ESC-derived cells lack innate immunity to a wide range of infectious agents and inflammatory cytokines. When used in patients, ESC-derived cells would be placed in wounded sites that are exposed to various pathogens and inflammatory cytokines; therefore, their viability and functionality would be significantly compromised if the cells...