Stephen Hanessian, Simon Giroux, Bradley L. Merner

Gebundenes Buch

Design and Strategy in Organic Synthesis

From the Chiron Approach to Catalysis

Beschreibung

Lange erwartet, fachlich erstklassig ... und erfrischend anders: Stephen Hanessian, einer der weltweit führenden Experten für organische Synthesechemie, diskutiert in diesem Band seine Sicht der Synthese. Nach einer allgemeinen und motivierenden Einführung erläutert er die Darstellung enantiomerenreiner Verbindungen, den Chiron-Ansatz, die Analyse von Substrukturen, die Auswahl von Vorläuferverbindungen und natürlich die Syntheseplanung am Computer. Ein übersichtlicher Anhang fasst Reaktionen von Aminosäuren, Kohlenhydraten, Hydroxysäuren und Terpenen zusammen.

Autor

Stephen Hanessian holds the Isis Pharmaceutical Research Chair at the University of Montreal and is also on the faculty of the Departments of Chemistry, Pharmaceutical Sciences and Pharmacology at the University of California, Irvine. He has received numerous awards and distinctions, the latest being the 2012 Ernest Guenther Award in the Chemistry of Natural Products from the American Chemical Society, and the IUPAC-Richter-Preis in Medicinal Chemistry.

Simon Giroux was born and raised in Montreal, Canada. He received his PhD in 2006 with Prof. Stephen Hanessian and subsequently spent 2 years in the laboratory of Prof. E. J. Corey at Harvard University, as an NSERC postdoctoral fellow. He is currently working as a medicinal chemist at Vertex Pharmaceuticals in Cambridge, Massachusetts.

Bradley L. Merner is a native of St. John's, Newfoundland, Canada. He completed is PhD degree under the direction of Prof. Graham J. Bodwell at Memorial University in 2010, and then moved to the University of Montreal as postdoctoral research associate in the laboratories of Prof. Stephen Hanessian. In the fall of 2013 he will join the Department of Chemistry and Biochemistry at Auburn University as an Assistant Professor.

Produktdetails

• Verlag: Wiley-VCH
• 1. Auflage
• Seitenzahl: 828
• Erscheinungstermin: 30. Juli 2013
• Abmessung: 240mm x 170mm
• Gewicht: 1670g
• ISBN-13: 9783527333912
• ISBN-10: 3527333916
• Artikelnr.: 35259099