Design and development of nano based ophthalmic drug delivery system
Joshi Hardik
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Design and development of nano based ophthalmic drug delivery system

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Eye as a target for the drug delivery systems presents some unique challenges owing to its physiologic and anatomical characteristics. Systemic administration of drugs for ocular effect necessitates large doses to achieve sufficient concentration in the ocular tissues, leading to unwanted side effects. Though it is more convenient to administer the drugs directly into the exterior cu de sac of the eye, this approach suffers from poor residence time and consequently limited corneal permeation. Prednisolone acetate (PA) is a topical anti-inflammatory agent used in the treatment of steroid-respon...