Descriptive and analytical epidemiology of breast cancer

Descriptive and analytical epidemiology of breast cancer

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Breast cancer is the first cancer of women in the world and in Tunisia. Its incidence is in continuous rise.The risk factors of breast cancer are multiple. There are endogenous and exogenous hormonal factors, factors related to reproduction, demographic and breast factors, environmental factors and hereditary factors. Although the majority of cases are sporadic, it is estimated that 5-10% of cases have an inherited component. Two major susceptibility genes have been identified, BRCA1 (Breast CAncer 1) and BRCA2 (Breast CAncer 2), which play a key role in the DNA error repair process. Constitut...