Depressive symptoms in schizophrenia
Ciaran Mulholland
Broschiertes Buch

Depressive symptoms in schizophrenia

A review and an exploration of the aetiological importance of decreased serotoninergic function

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Depressive symptoms are common in individuals with schizophrenia. In this book the literature regarding the aetiology of such symptoms is reviewed and it is postulated that they may sometimes result from decreased serotoninergic function. Three studies were carried out to test this hypothesis. In the first patients with chronic schizophrenia were assessed for the presence of depressive symptoms. In the second patients with chronic schizophrenia and depressive symptoms were entered into a randomised controlled trial of sertraline, a SSRI antidepressant. In a third study patients with stable chr...