Cyclodextrin Complexes of Rosuvastatin Calcium
Astha Kuhad
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Cyclodextrin Complexes of Rosuvastatin Calcium

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Statins are the treatment of choice for the management of dyslipidemia /hypercholesterolaemia because of their proven efficacy and safety profile. They also have an increasing role in managing cardiovascular risk in patients with relatively normal levels of plasma cholesterol. Although all statins share a common mechanism of action, they differ in terms of their chemical structures, pharmacokinetic profiles, and lipid-modifying efficacy. The chemical structures of statins govern their water solubility, which in turn influences their absorption, distribution, metabolism and excretion. Most of t...