Connective Tissue Growth Factor in eye development of mice
Amin Abdou Seleem Mohamed
Broschiertes Buch

Connective Tissue Growth Factor in eye development of mice

The role of connective tissue growth factor during eye development of mice discussed by transgenic and knockout mice

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The present study was designed and carried out to investigate the role of connective tissue growth factor (CTGF) during eye development of CD1 mice at pre- and postnatal stage by using different technique as Real time PCr and Immunohistochemistry In conclusion CTGF is essential for life and absence of this gene lead to the death, Knockout homozygous CTGF -/- severe from a lot of abnormalties during prenatal stages until death. The over-expression CTGF transgenic mice with high concentration in line 6 showed a disappearance of the ciliary body processes, while the moderate over-expression CTGF ...