Computer Methods, Part C

Volume 487
Herausgegeben:Simon, Melvin I.; Brand, Ludwig

• Gebundenes Buch

Produktbeschreibung

The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with the 2 previous Computer Methods volumes for the methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research.

Produktdetails

• Methods in Enzymology Volume 487
• Verlag: Academic Press
• Artikelnr. des Verlages: C2009-0-62380-1
• Seitenzahl: 696
• Erscheinungstermin: 12. Januar 2011
• Englisch
• Abmessung: 240mm x 161mm x 43mm
• Gewicht: 1240g
• ISBN-13: 9780123812704
• ISBN-10: 0123812704
• Artikelnr.: 32778717

Inhaltsangabe

1. Predicting Fluorescence Lifetimes and Spectra of Biopolymers


Patrik R. Callis


2. Modeling of Regulatory Networks: Theory and Applications in the study of the Drosophila Circadian Clock


Elizabeth Y. Scribner, Hassan M. Fathallah-Shaykh


3. Strategies for articulated multibody-based adaptive coarse grain simulation of RNA


Mohammad Poursina, Kishor D. Bhalerao, Samuel C. Flores , Kurt S. Anderson, Alain Laederach


4. Modeling Loop Entropy


Gregory S. Chirikjian


5. Inferring Functional Relationships and Causal Network Structure from Gene Expression Profiles


Radhakrishnan Nagarajan


6. Numerical solution of the chemical master equation: uniqueness and stability of the stationary distribution for chemical networks, and mRNA bursting in a gene network with negative feedback regulation


E. S. Zeron, M. Santill_an


7. How molecular should your molecular model be? On the level of molecular detail required to simulate biological networks in systems and synthetic biology


Didier Gonze, Wassim Abou-Jaoud´e, Adama Ouattara, and Jos´e Halloy


8. Computational modelling of biological pathways by executable biology


Maria Luisa Guerriero John K. Heath


9. Computing Molecular Fluctuations in Biochemical Reaction Systems Based on A Mechanistic, Statisitical Theory of Irreversible Processes


Don Kulasiri


10. Probing the input-output behaviour of biochemical and genetic systems: system identification methods from control theory


David McMillen, Brian Ingalls, Jordan Ang


11. Biochemical pathway modelling tools for drug target detection in cancer and other complex diseases


Alberto Marin-Sanguino, Shailendra K. Gupta, Eberhard O. Voit and Julio Vera


12. Deterministic and Stochastic Simulation and Analysis of Biochemical Reaction Networks: The Lactose Operon Example


Necmettin Yildirim, Caner Kazanci F


13. Multivariate Neighborhood Sample Entropy: A method for data reduction and prediction of complex data.


Joshua S. Richman MD, PhD


14. Scaling differences of heartbeat excursions between wake and sleep periods


L. Guzm´an-Vargas, I. Reyes-Ram´irez, R. Hern´andez-P´erez, F. Angulo-Brown


15. Changepoint analysis for single-molecule polarized totalinternal reflection fluorescence microscopy experiments


John F. Beausang, Yale E. Goldman, and Philip C. Nelson


16. Inferring mechanisms from dose-response curves


Carson C. Chow, Karen M. Ong, Edward J. Dougherty, and S. Stoney Simons, Jr.


17. Spatial Aspects in Biological System Simulations


Haluk Resat, Michelle N. Costa, and Harish Shankaran


18. Computational Approaches to Modeling Viral Structure and Assembly


Stephen C. Harvey, Anton S. Petrov, Batsal Devkota and Mustafa Burak Boz


19. An Object-Oriented Software Suite for the Simulation and Design of Macromolecules


Andrew Leaver-Fay, Michael Tyka, Steven M. Lewis, Oliver F. Lange, James Thompson, Ron Jacak, Kristian Kaufman, P. Douglas Renfrew, Colin A. Smith, Will Sheffler, Ian W. Davis, Seth Cooper, Adrien Treuille, Daniel J. Mandell, Florian Richter, Yih-En Andrew Ban, Sarel J. Fleishman, Jacob E. Corn, David E. Kim, Sergey Lyskov, Monica Berrondo, Stuart Mentzer, Zoran Popovic, James J. Havranek, John Karanicolas, Rhiju Das, Jens Meiler, Tanja Kortemme, Jeffrey J. Gray, Brian Kuhlman¹, David Baker, and Philip Bradley


20. Computational Design of Intermolecular Stability and Specificity in Protein Self-Assembly

Vikas Nanda, Sohail Zahid, Fei Xu, Daniel Levine