Computational Methods for Protein Structure Prediction and Modeling

Volume 1: Basic Characterization

Herausgegeben: Xu, Ying; Xu, Dong; Liang, Jie
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An ultimate goal of modern biology is to understand how the genetic blueprint of cells(genotype)determinesthestructure,function,andbehaviorofalivingorganism (phenotype). At the center of this scienti?c endeavor is characterizing the bioch- ical and cellular roles of proteins, the working molecules of the machinery of life. A key to understanding of functional proteins is the knowledge of their folded str- tures in a cell, as the structures provide the basis for studying proteins' functions and functional mechanisms at the molecular level. Researchers working on structure determination have tra...