Comparative Evaluation of Micronuclei in OPMD using special stains
Neha GuptaSachin Sachdeva
Broschiertes Buch

Comparative Evaluation of Micronuclei in OPMD using special stains

Micronuclei : A prognostic Biomarker

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Micronuclei (MNs) are extranuclear cytoplasmic DNA bodies which are induced in cells by numerous genotoxic agents that damage chromosome. The MN assay in exfoliated buccal cells is a useful and minimally invasive method for monitoring genetic damage. Buccal cell micronuclei (MNs) are a putative biomarker for oral cancer risk as evidence suggests that MNs are significantly elevated in buccal mucosal cells of persons who harbor precancerous lesions and in cancer patients. It serves as a tool for early detection of cancerous and precancerous lesions. Various stains have been used for the same, bu...