Cloning, heterologous expression and partial purification of IF2
Aleksei Kovalev
Broschiertes Buch

Cloning, heterologous expression and partial purification of IF2

Cloning, heterologous expression and purification of the IF2 translation initiation factor (Mycobacterium tuberculosis)

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It is important to evaluate the role of the IF2 within the bacterial translation regulatory mechanism as well as to pose the IF2 as a molecular target for repurposed non-steroidal anti-inflammatory drugs (NSAIDS). The aim of this project is to identify a novel and an effective therapeutic endogenous molecular target in Mycobacterium tuberculosis. In this study, I have identified, cloned, expressed and partially purified the novel putative endogenous therapeutic target for various non-steroidal anti-inflammatory drugs (NSAIDs) from H37Rv strain of Mycobacterium tuberculosis: putative mycobacter...