CHIRAL SEPARATION, CAPILLARY ELECTROPHORESIS
Khaldun al Azzam
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CHIRAL SEPARATION, CAPILLARY ELECTROPHORESIS

SEPARATION OF CHLOROQUINE AND ITS ENANTIOMERS IN PHARMACEUTICALS USING CAPILLARY ELECTROPHORESIS TECHNIQUE

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Currently, there is considerable interest in the synthesis and separation of enantiomeric compounds because of their importance in biochemistry, pharmaceutical, etc. Frequently the analytical methods used for the enantiomeric separations, for the monitoring the progress of asymmetric synthesis or establishing the optical purity of the products are chromatography. More recently capillary electrophoresis (CE) has been added to the list. CE is an interesting technique that shows promise for the resolution of enantiomers. This is accomplished by adding to the background electrolyte with suitable c...