Changes in testes of Swiss albino mice exposed to gamma radiation
Biochemical, electrophoreticand cytogenetic evaluation
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The present investigations provide base line and significant information on the effect of various doses of gamma radiation on the testicular biochemical milieu.These are manifested by changes in the estimates of total protein, triglyceride, alkaline and acid phosphatase and lactate dehydrogenase. Agar gel electrophoretic resolution of LDH isoenzymes provide clues to the changes in the bioenergetics of the testes. Further studies were also made on the alterations in the mitotic index, and on the morphological changes in the chromosomes of bone marrow cells. These indicate the extent of damage t...
The present investigations provide base line and significant information on the effect of various doses of gamma radiation on the testicular biochemical milieu.These are manifested by changes in the estimates of total protein, triglyceride, alkaline and acid phosphatase and lactate dehydrogenase. Agar gel electrophoretic resolution of LDH isoenzymes provide clues to the changes in the bioenergetics of the testes. Further studies were also made on the alterations in the mitotic index, and on the morphological changes in the chromosomes of bone marrow cells. These indicate the extent of damage to the genomic apparatus due to different doses of gamma radiation in Swiss albino mice.
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