Cellular import and export of free and protein-bound vitamin B12
Rasmus Beedholm-Ebsen
Broschiertes Buch

Cellular import and export of free and protein-bound vitamin B12

A medical book

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This book is based on experimental work performed at Aarhus University. The work was conducted to gain insight into the cellular endocytosis and export of vitamin B12. Vitamin B12 (cobalamin) is an organic molecule which functions as an essential coenzyme for two metabolic reactions in mammalians. Cellular vitamin B12 uptake is a complex process involving different binding proteins and receptors. The studies revealed that the endocytosis of transcobalamin bound to fluorescent vitamin B12 conjugate is correlated with cell growth in fast dividing cancer cells and the uptake of free vitamin B12 w...