Cefixime Trihydrate Sustained Release Matrix Tablet
Parth PatelKinjal Patel
Broschiertes Buch

Cefixime Trihydrate Sustained Release Matrix Tablet

To study the effect of different viscosity grade of HPMC on Cefixime Trihydrate sustained Release Matrix Tablet

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The present work aims to study effect of diff. viscosity grade of HPMC on cefixime trihydrate sustained release matrix tablet with a view to prolong drug release in vivo & reduce frequency of dosing. Cefixime Trihydrate is an orally active third generation cephalosporin and active against Gram+ve as well as Gram -ve bacteria. It has plasma half-life of 3-4 hrs. The Sustained release matrix tablets were prepared by wet granulation method using diff. grade of HPMC, Lactose, MCC & PVP K-30. The granules were subjected to pre-compression & post-compression parameters and they were in the acceptabl...