Cationic, Lipidic, and Hybrid Amino- and Guanidinoglycoside Conjugates
Aurora Sganappa
Broschiertes Buch

Cationic, Lipidic, and Hybrid Amino- and Guanidinoglycoside Conjugates

Synthesis, Antibacterial Activity and Cellular Uptake of New non-Viral Vectors for Gene and Drug Delivery

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In recent years new non-viral vectors for gene and drug delivery have become more and more important in order to overcome the use of viral vectors, due to their potential dangerous drawbacks, and facilitate drug entery into cells. Aminoglycosides with guanidinoglycosides, their derivatives, are a large family of well-known potent antibiotics. The objetive of this work was the use of aminoglycosides for the development of: new multifunctional gene delivery vectors, new multivalent carriers for drug delivery and a small collection of new antibiotics. So, different kind of non-viral vectors for g...