Brain Somatic Cross-Talk and the Central Control of Metabolism

Brain Somatic Cross-Talk and the Central Control of Metabolism

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In mammals, a robust physiologic system acts to maintain relative constancy of weight. A key element of this system is leptin. The nature of this "brain-somatic" cross talk is as yet poorly understood, but it is likely to have important implications for the pathophysiology and treatment of obesity, diabetes and other metabolic disorders.