Gebundenes Buch

Brain Development in Drosophila melanogaster

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The central nervous system (CNS) represents the organ with the highest struc tural and functional complexity. Accordingly, uncovering the mechanisms leading to cell diversity, patterning and connectivity in the CNS is one ofthe major chal lenges in developmental biology. The developing CNS of the fruitfly Drosophila melanogaster is an ideal model system to study these processes. Several principle questions regarding neurogenesis (like stem cell formation, cell fate specification, axonal pathfinding) have been addressedinDrosophilaby focusing on the relatively simply structuredtruncal partsofth...