Biomarkers of Tumor Metastasis and Invasiveness
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Biomarkers of Tumor Metastasis and Invasiveness

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The molecular characterization of tumors, investigated particularly through proteogenomic analyses, has led to a revolution in cancer research. Over the last decade, the development of quantitative proteomics, together with other major technological breakthroughs, have identified candidate biomarkers for diagnosis, prognosis, and drug efficacy/resistance follow-up. These improvements have allowed researchers to explore the capability of cancer cells to invade, metastasize, and finally, destroy normal tissues and organs. In parallel, new hypotheses have been formulated, and the means cancer cel...