Bioinformatic view of kinesin super-family and structure of kinesin-1
Xiao Liu
Broschiertes Buch

Bioinformatic view of kinesin super-family and structure of kinesin-1

large scale analysis of kinesin super-family and structural changes from a closed to an open state of the motor domain of kinesin-1

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Kinesins form a large microtubule-associated motor protein super-family that can be found in every eukaryotic genome sequenced so far. Not only is the translocation of a large number of organelles, protein complexes and mRNAs carried out by them, but also the formation of the meiotic spindle and mitotic spindle integrity are strongly dependent on the kinesins. To understand the kinesins, we have to answer many questions, such as how many sub-families are there in kinesin super-family; what is the commonesses and differences among kinesin sub-families; how to classify kinesins and determine the...