
Bile Acids
Toxicology and Bioactivity
Herausgeber: Jenkins, Gareth J; Hardie, Laura
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Bile acids are increasingly being seen as extremely important carcinogenic agents in cancers of the bile duct, liver, colon, rectum, and oesophagus. In recent years there have been tremendous advances in the understanding of the mechanisms behind the toxicity and bioactivity of different Bile acids and these are covered at length in this book. Prior to the publication of this book there was no single source of information on the toxicology and bioactivity properties of Bile acids and the book uniquely collects all the relevant information together regarding the role of Bile acids in human dise...
Bile acids are increasingly being seen as extremely important carcinogenic agents in cancers of the bile duct, liver, colon, rectum, and oesophagus. In recent years there have been tremendous advances in the understanding of the mechanisms behind the toxicity and bioactivity of different Bile acids and these are covered at length in this book. Prior to the publication of this book there was no single source of information on the toxicology and bioactivity properties of Bile acids and the book uniquely collects all the relevant information together regarding the role of Bile acids in human disease. Additionally, as Bile acids are synthesised from cholesterol, there is wide recognition of the role for Bile acids in obesity linked diseases and this is also covered in this new publication. The book is edited by two experts in the field who have been involved in Bile acid research for several years and who are closely involved with major research groups in the UK, Europe and the US actively engaged in Bile acid research. The book also includes contributions by experts in the field and this book will appeal to all researchers who wish to understand the basic toxicology and bioactivity of Bile acids.