Gebundenes Buch

Big Data in Predictive Toxicology

Beschreibung

The rate at which toxicological data is generated is continually becoming more rapid and the volume of data generated is growing dramatically. This is due in part to advances in software solutions and cheminformatics approaches which increase the availability of open data from chemical, biological and toxicological and high throughput screening resources. However, the amplified pace and capacity of data generation achieved by these novel techniques presents challenges for organising and analysing data output. Big Data in Predictive Toxicology discusses these challenges as well as the opportunities of new techniques encountered in data science. It addresses the nature of toxicological big data, their storage, analysis and interpretation. It also details how these data can be applied in toxicity prediction, modelling and risk assessment. This title is of particular relevance to researchers and postgraduates working and studying in the fields of computational methods, applied and physical chemistry, cheminformatics, biological sciences, predictive toxicology and safety and hazard assessment.

Autor

Daniel Neagu is Professor of Computing with the University of Bradford, where he leads the Artificial Intelligence Research Group. Daniel is Fellow of the Higher Education Academy, and also member of the Institute of Electrical and Electronics Engineers: Computer Society and Computational Intelligence Society, the Association for Computing Machinery and the British Computer Society. Daniel Neagu studies the integration of explicit and implicit knowledge with means of computational intelligence. Daniel Neagu's research on machine learning, data mining, data quality and applications to product safety, predictive toxicology and engineering analytics has been published in more than 100 peer-reviewed conferences and journals, and funded by national and international research councils, organisations and industry. Dr Andrea Richarz holds a diploma and PhD in Chemistry from the Technical University Berlin. She has managed two large international EU research projects in the area of computational toxicology and new approaches for chemical safety assessment, related to REACH chemicals and cosmetics substances, and was also involved in nanosafety project research. As Scientific Officer at the European Commission Joint Research Centre in Ispra, Italy she worked in the area of predictive toxicology, in silico methods and read-across, with special interest in integrated chemical safety assessment approaches as well as combined exposure to chemicals, including uncertainties of and confidence in the approaches in view of their regulatory acceptance. She has recently joined the European Chemicals Agency in Helsinki.

Produktdetails

• Verlag: RSC Publishing
• Seitenzahl: 414
• Erscheinungstermin: 10. Dezember 2019
• Englisch
• Abmessung: 234mm x 163mm x 30mm
• Gewicht: 771g
• ISBN-13: 9781782622987
• ISBN-10: 1782622985
• Artikelnr.: 52710901