Beyond Single Genes: The Role of Multiple Variants in Complex Disease
Eliot
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Beyond Single Genes: The Role of Multiple Variants in Complex Disease

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For a long time, we thought diseases flipped on like light switches, controlled by a single faulty gene. But the reality is far more intricate. This article explores how multiple gene variations, not just one, can influence complex diseases.Imagine a tangled web - that's how researchers now view complex diseases like heart disease or diabetes. Each strand represents a genetic variant, a slight difference in a gene's DNA. While each variant might have a small effect, multiple variants working together can significantly increase disease risk.This concept, called polygenic inheritance, sheds ligh...