Robert C. Elston, William Johnson

Basic Biostatistics for Geneticists and Epidemiologists

A Practical Approach

• Broschiertes Buch

Produktbeschreibung

Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus this fast moving field. Unlike many other elementary books on biostatics, the main focus of this book is to explain basic concepts needed to understand statistical procedures.

This Book:
_ Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares.
_ Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research.
_ Is illustrated throughout with simple examples to clarify the Statistical methodology.
_ Explains Bayes' Theorem pictorially.
_ Features exercises, with answers to alternate questions, enabling use as a course text.

Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researches and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.

Produktdetails

• Verlag: Wiley & Sons
• Artikelnr. des Verlages: 14502490000
• 1. Auflage
• Seitenzahl: 384
• Erscheinungstermin: 1. Dezember 2008
• Englisch
• Abmessung: 244mm x 170mm x 21mm
• Gewicht: 665g
• ISBN-13: 9780470024904
• ISBN-10: 0470024909
• Artikelnr.: 22546211

Autorenporträt

Robert C. Elston Department of Epidemiology and Biostatistics, Case Western Reserve University, USA. William D. Johnson Pennington Biomedical Research Center, Louisiana State University, USA.

Inhaltsangabe

Preface. 1. Introduction: The role and Relevance of Statistics, Genetics
and Epidemiology In Medicine. 2. Populations, Samples, and Study Design. 3.
Descriptive Statistics. 4. The Laws of Probability. 5. Random Variables and
Distributions. 6. Estimates and Confidence Limits. 7. Significance Tests
and Tests of Hypotheses. 8. Likelihood Ratios, Bayesian Methods and
Multiple Hypotheses. 9. The Many Uses of Chi-Square. 10. Correlation and
Regression. 11. Analysis of Variance and Linear Models. 12. Some
Specialized Techniques. 13. Guides to a Critical Evaluation of Published
Reports. Epilogue. Review Problems. Answers to Odd-Numbered Problems.
Appendix. Index.

Rezensionen

"This is a well written and comprehensive review of the basic (and not so basic) concepts and techniques in biostatistics. It is understandable to biologists and clinicians, while still providing useful pointers and reminders to statisticians. It is worth a place on the bookshelves of all researchers in genetics, regardless of their statistical expertise." ( Human Genetics, February 2010)