Autoreactive T cells in Systemic Lupus Erythematosus
Dimas Abdirama
Broschiertes Buch

Autoreactive T cells in Systemic Lupus Erythematosus

Their role in disease pathogenesis and as therapeutic tool

Versandkostenfrei!
Versandfertig in 6-10 Tagen
62,99 €
inkl. MwSt.
PAYBACK Punkte
31 °P sammeln!
Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disorder characterized by loss of immune tolerance towards nuclear autoantigens such as SmD1, RNP70, Histone, Ro, and La. Although great progress towards our understanding of the disease has been made over the past 50 years and mortality is currently only around 10% within the last ten years, our knowledge of the factors that drive the pathology of SLE is still limited. The role of CD4+ T cells specific to nuclear antigens in the disease pathogenesis of SLE is yet not fully known because the detection of human autoreactive...