Auditory Signal Processing

Physiology, Psychoacoustics, and Models

Herausgegeben: Pressnitzer, Daniel; de Cheveigne, Alain; McAdams, Stephen; Collet, Lionel
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The sensory hair cells in the inner ear and vestibular system convert

mechanical stimuli, sound and motion into neural activity that is

responsible for the sensations of hearing, motion and head position.

In mammals, the loss of hair cells from acoustic overstimulation,

ototoxic drugs and aging is irreversible, leading to a permanent loss

of function. However, it is now clear that hair cells in other

vertebrates are capable of regenerating and recovering partial or

complete function. Moreover, partially damaged hair cells can undergo

self-repair or be protected from traumatic insults by external

compounds. This volume provides a comprehensive survey of what is

currently known about the regeneration, repair and protection of

sensory hair cells and subsequent recovery of function in the auditory

and vestibular system. The aim is to provide graduate students,

postdoctoral fellows, clinicians and scientists in related disciplines

with the biological bases of hair cells and with an understanding of

the factors that contribute to their regeneration and repair.