Assay Sensitivity
Clinical trial, Therapy, Efficacy, Scientific control
Herausgegeben: Christer, Emory
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Assay sensitivity is a property of a clinical trial defined as the ability of a trial to distinguish an effective treatment from a less effective or ineffective intervention. Without assay sensitivity, a trial is not internally valid and is not capable of comparing the efficacy of two interventions.Lack of assay sensitivity has different implications for trials intended to show a difference greater than zero between interventions (superiority trials) and trials intend...
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Assay sensitivity is a property of a clinical trial defined as the ability of a trial to distinguish an effective treatment from a less effective or ineffective intervention. Without assay sensitivity, a trial is not internally valid and is not capable of comparing the efficacy of two interventions.Lack of assay sensitivity has different implications for trials intended to show a difference greater than zero between interventions (superiority trials) and trials intended to show non-inferiority. Non-inferiority trials attempt to rule out some margin of inferiority between a test and control intervention i.e rule out that the test intervention is no worse than the control intervention by a chosen amount.
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