Applications of Dendrimers in Drug Delivery
Principles and Approaches
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Dendrimers are spherical and repetitively branched molecules polymeric molecules. The name of dendrimers comes from two words, Greek word dendron, meaning tree and meros, meaning parts. Dendrimers consist of a core molecule and alternating layers of two monomers. The physical characteristics of dendrimers, including their monodispersity, water solubility, encapsulation ability, and large number of functionalizable peripheral groups, make these macromolecules appropriate candidates for evaluation as drug delivery, diagnostic, gene delivery and chemotherapy. There are several routs of administra...
Dendrimers are spherical and repetitively branched molecules polymeric molecules. The name of dendrimers comes from two words, Greek word dendron, meaning tree and meros, meaning parts. Dendrimers consist of a core molecule and alternating layers of two monomers. The physical characteristics of dendrimers, including their monodispersity, water solubility, encapsulation ability, and large number of functionalizable peripheral groups, make these macromolecules appropriate candidates for evaluation as drug delivery, diagnostic, gene delivery and chemotherapy. There are several routs of administration, including intravenous and oral. There are two defined methods of dendrimer synthesis, divergent synthesis and convergent synthesis.
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