APOPTOSIS

APOPTOSIS

Apoptosis may be one mechanism underlying the pathophysiology involved with the progression of periodontitis.

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Apoptosis is regarded as a carefully regulated energy dependent process, characterized by specific morphological and biochemical features in which caspase activation plays a central role. Although many of the key apoptotic proteins that are activated or inactivated in the apoptotic pathways have been identified, the molecular mechanisms of action or activation of these proteins are not fully understood and are the focus of continued research. The importance of understanding the mechanistic machinery of apoptosis is vital because programmed cell death is a component of both health and disease, ...