Antioxidant and Anti-ulcer Activities of Extracts from Tapinanthus
Dodoneifolius on Aspirin Induced Gastric Ulcer in Rats
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Peptic ulcer or Dyspepsia is one of the global`s diseases which causes mortality throughout the world, touching the lives of millions of peoples. For many years excess acid was believed to cause peptic ulcer. This misconception was suddenly illuminated due to the discovery of Helicobacter pylori bacteria which play a great role in the cause of peptic ulcer disease. To treat peptic ulcer natural products and modern synthetic drugs are in used but, still a complete cure has not been discovered and exploration of new antiulcer drugs has remain a field of active research. In this research a ground...
Peptic ulcer or Dyspepsia is one of the global`s diseases which causes mortality throughout the world, touching the lives of millions of peoples. For many years excess acid was believed to cause peptic ulcer. This misconception was suddenly illuminated due to the discovery of Helicobacter pylori bacteria which play a great role in the cause of peptic ulcer disease. To treat peptic ulcer natural products and modern synthetic drugs are in used but, still a complete cure has not been discovered and exploration of new antiulcer drugs has remain a field of active research. In this research a ground leaves of Tapinanthus dodoneifolius were macerated. The fractions obtained where subjected to phytochemicals screening, Antioxidant activity using DPPH and Antiulcer activity using an in vivo method on small animals. Causes, symptoms and treatment of peptic ulcer disease were discussed. The study has been a contribution to the assessment of possible antioxidant and antiulcer substances and should be useful to Biologist, Biochemists, Chemists, Health workers and other Medical practitioners.
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