Analytical Method Development of Artesunate
In Pharmaceutical Tablet Formulations
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Drug analysts play an indirect but very important role in creating the basis for highly efficient drug therapy. The quality of commercially available drugs varies greatly among countries. Due to lack of regulations and poor quality control practices in some countries, the amount of the active ingredient can be inconsistent. Poor formulation techniques can affect the release of active ingredients from a tablet, with some tablets releasing very little if any drug. Since analysis is an important development of any dosage form, it necessary to have a simple, precise, accurate and sensitive method ...
Drug analysts play an indirect but very important role in creating the basis for highly efficient drug therapy. The quality of commercially available drugs varies greatly among countries. Due to lack of regulations and poor quality control practices in some countries, the amount of the active ingredient can be inconsistent. Poor formulation techniques can affect the release of active ingredients from a tablet, with some tablets releasing very little if any drug. Since analysis is an important development of any dosage form, it necessary to have a simple, precise, accurate and sensitive method for assay of any drug product both as a bulk and in its formulation. The increasing level of use of Artesunate and Artesunate combination tablets as a result of its versatility in the management of various cases of malarial infections necessitated the need to evaluate the quality of the various brands available. The development of simple and cost-effective analytical protocols for Artemisinin and its derivatives in both pure form and in dosage form has become very important in the face of increasing supply and demand for this antimalarial agent.
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