Analytical Method Development & validation
Shefali Rana
Broschiertes Buch

Analytical Method Development & validation

Of Lafutidine and Domperidone

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We determine Lafutidine and Domperidone simultaneously by simple, rapid, accurate and precise UV-Spectroscopic methods, HPLC, and HPTLC. First Order Derivative method was based on the fact that LAF and DOM showed one zero crossing points 286.60 nm and 273.20 nm respectively. The estimation of both drugs by these two wavelength. Area under Curve Method was done by taking area under the curve in the range of 273 ± 5nm and 287.2 ± 5nm was selected for the analysis for LAF and DOM. The absorptivity values calculated. The calibration curve was plotted regression equation was calculated. HPLC meth...