An review update on MMP
MMP inside out
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Matrix metallopeptidase (MMPs), also known as matrix metalloproteinase or matrixins, are metalloproteinase that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily. Out of which, MMP-2 and MMP9 are involved in all of the pathological processes mentioned above, both during the development of the dental germ and through their influence on the proliferation and invasion of odontogenic tumors, their participation in the degradation of dental and peri...
Matrix metallopeptidase (MMPs), also known as matrix metalloproteinase or matrixins, are metalloproteinase that are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily. Out of which, MMP-2 and MMP9 are involved in all of the pathological processes mentioned above, both during the development of the dental germ and through their influence on the proliferation and invasion of odontogenic tumors, their participation in the degradation of dental and periodontal tissues by promoting the formation of a carious lesion, gingivitis and periodontitis; confirming that this family of proteins can play a major role in various oral biological processes. Moreover, this means that MMPs are currently considered significant biomarkers for research in the different areas of specialization.
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