An Introduction to Medicinal Chemistry
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Reviews- 'Review from previous edition "There is excellent all-round coverage here for both undergraduates and postgraduate researchers ... This is a textbook which should be used throughout all medicinal chemistry courses."' -Chemistry & Industry 2002 - '"In summary Patrick is in my opinion the best text support for a Medicinal Chemistry programme and it continues to be better and better with each review..."' -Stuart Warriner, University of Leeds, 2004Description - The lively, reader-friendly writing style makes a complex subject readily accessible to all students, regardless of ability - An ...
Reviews
- 'Review from previous edition "There is excellent all-round coverage here for both undergraduates and postgraduate researchers ... This is a textbook which should be used throughout all medicinal chemistry courses."' -Chemistry & Industry 2002
- '"In summary Patrick is in my opinion the best text support for a Medicinal Chemistry programme and it continues to be better and better with each review..."' -Stuart Warriner, University of Leeds, 2004
Description
- The lively, reader-friendly writing style makes a complex subject readily accessible to all students, regardless of ability
- An interdisciplinary treatment of medicinal chemistry assumes little background knowledge, making the book invaluable to a broad range of students
- Key points, an expanded glossary, further reading lists, and end of chapter questions all make the book an even more effective one to learn from
- Boxed examples which show how the concepts of medicinal chemistry underlie the development of modern drugs, illustrating how the theory of medicinal chemistry is applied in practice
- A new two-colour text design increases the clarity of figures, which greatly enhance the explanation of difficult concepts
- Companion web site includes figures available to download, to facilitate lecture preparation, and 3D molecular structures plus multiple choice questions, to encourage and support independent learning
Many of us think nothing of taking a painkiller to ease a headache, or to relieve the symptoms of 'flu. But how do drugs have their effect in the human body? How are new drugs discovered and designed to be as effective as possible? An Introduction to Medicinal Chemistry offers an engaging insight into the one field of chemistry which arguably has the greatest impact on our quality of life than any other.
Contents
- PART A
- Pharmacodynamics and pharmacokinetics
- 1 Drugs and the medicinal chemist
- 2 The why and the wherefore - drug targets
- 3 Proteins as drug targets
- 4 Proteins as drug targets - enzymes
- 5 Proteins as drug targets - receptors
- 6 Proteins as drug targets - receptor structure and signal transduction
- 7 Nucleic acids as drug targets
- 8 Pharmacokinetics and related topics
- PART B
- Drug discovery, design and development
- 9 Drug discovery - finding a lead
- 10 Drug design - pharmacodynamics
- 11 Drug design - pharmacokinetics
- 12 Drug development
- PART C
- Tools of the trade
- 13 Quantitative structure-activity relationships (QSAR)
- 14 Combinatorial synthesis
- 15 Computers in medicinal chemistry
- PART D
- Topics in medicinal chemistry
- 16 Antibacterial agents
- 17 Antiviral drugs
- 18 Anticancer agents
- 19 The peripheral nervous system - cholinergics, anticholinergics, and anticholinesterases
- 20 The adrenergic nervous system
- 21 The opium analgesics
- 22 Anti-ulcer agents
- 'Review from previous edition "There is excellent all-round coverage here for both undergraduates and postgraduate researchers ... This is a textbook which should be used throughout all medicinal chemistry courses."' -Chemistry & Industry 2002
- '"In summary Patrick is in my opinion the best text support for a Medicinal Chemistry programme and it continues to be better and better with each review..."' -Stuart Warriner, University of Leeds, 2004
Description
- The lively, reader-friendly writing style makes a complex subject readily accessible to all students, regardless of ability
- An interdisciplinary treatment of medicinal chemistry assumes little background knowledge, making the book invaluable to a broad range of students
- Key points, an expanded glossary, further reading lists, and end of chapter questions all make the book an even more effective one to learn from
- Boxed examples which show how the concepts of medicinal chemistry underlie the development of modern drugs, illustrating how the theory of medicinal chemistry is applied in practice
- A new two-colour text design increases the clarity of figures, which greatly enhance the explanation of difficult concepts
- Companion web site includes figures available to download, to facilitate lecture preparation, and 3D molecular structures plus multiple choice questions, to encourage and support independent learning
Many of us think nothing of taking a painkiller to ease a headache, or to relieve the symptoms of 'flu. But how do drugs have their effect in the human body? How are new drugs discovered and designed to be as effective as possible? An Introduction to Medicinal Chemistry offers an engaging insight into the one field of chemistry which arguably has the greatest impact on our quality of life than any other.
Contents
- PART A
- Pharmacodynamics and pharmacokinetics
- 1 Drugs and the medicinal chemist
- 2 The why and the wherefore - drug targets
- 3 Proteins as drug targets
- 4 Proteins as drug targets - enzymes
- 5 Proteins as drug targets - receptors
- 6 Proteins as drug targets - receptor structure and signal transduction
- 7 Nucleic acids as drug targets
- 8 Pharmacokinetics and related topics
- PART B
- Drug discovery, design and development
- 9 Drug discovery - finding a lead
- 10 Drug design - pharmacodynamics
- 11 Drug design - pharmacokinetics
- 12 Drug development
- PART C
- Tools of the trade
- 13 Quantitative structure-activity relationships (QSAR)
- 14 Combinatorial synthesis
- 15 Computers in medicinal chemistry
- PART D
- Topics in medicinal chemistry
- 16 Antibacterial agents
- 17 Antiviral drugs
- 18 Anticancer agents
- 19 The peripheral nervous system - cholinergics, anticholinergics, and anticholinesterases
- 20 The adrenergic nervous system
- 21 The opium analgesics
- 22 Anti-ulcer agents