Alternative Immune Monitoring Test for People Living with HIV/AIDS

Alternative Immune Monitoring Test for People Living with HIV/AIDS

Evaluation of the probability of using Total Lymphocyte Count as an alternative to CD4+ T cell count

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The AIDS epidemic has resulted in a tremendous cost in terms of loss of lives and life-quality worldwide, especially in Africa, where seventy percent of deaths from HIV-1 infection have occurred (UNAID and WHO 2004). In well-resourced settings, the decision to initiate ART is based predominantly on the presence of HIV-related symptoms and on CD4+ T-cell count (Badri and Wood 2003). Absolute CD4+ T-cell counts and CD4+ percentages have constituted the mainstay criteria for monitoring progression in HIV-1 infected patients. The measurement of CD4+ T cell count in developing country is very expen...