Admixture Dynamics, Natural Selection and Diseases in Admixed Populations
Wenfei Jin
Gebundenes Buch

Admixture Dynamics, Natural Selection and Diseases in Admixed Populations

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In this thesis, Dr. Jin presents the distribution of ancestral chromosomal segments in the admixed genome, which could provide the information needed to explore population admixture dynamics. The author derives accurate population histories of African Americans and Mexicans using genome-wide single nucleotide polymorphisms (SNPs) data. Mapping the genetic background facilitates the study of natural selection in the admixed population, and the author identifies the signals of selection in African Americans since their African ancestors left for America. He further demonstrates that many of the ...